Apply Nioxin System 1 Shampoo onto wet hair and scalp. Gently massage and rinse thoroughly with water. For best results, use daily in combination with Nioxin System 1 Conditioner. Why you'll love it: Clinically and dermatologically tested, the shampoo nourishes and gently cleanses your hair to prevent against follicle-clogging sebum, resulting in thicker, fuller hair.